Melanotan II 10mg (price is per vial)
$33.92 If paid in BTC $27.13
Melanotan II 10mg has to reconstituted with Bacteriostatic water (BAC).
Total amount of active ingredient: 10mg (1vial)
Availability: In stock
Top Color: Yellow
Shelf Life: 36 months
USA: $11.95 (3-5 business days)
International : $49.95 (7-14 business days)
If your shipment was seized (International Orders), we will provide a 50% discount applicable on your next purchase. Please contact us for more information.
Minimum Order: 1vial
Melanotan 2 (also referred to as Melanotan II) might be an artificially delivered variation of a peptide hormone normally created inside the body that animates melanogenesis, a procedure subject for pigmentation of the skin. This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors within the process of exerting its effects. To be sure, MSH likewise applies a powerful impact over lipid digestion, hunger, and sexual moxie by means of these melanocortin receptors. As a result, Melanotan 2 has been shown in studies to exhibit suppressant, lipolytic, and libido-enhancing effects additionally to promoting skin tanning. Melanotan 2 has been explored widely to be utilized in securing against the unsafe impacts of bright from daylight on account of its melanogenesis-animating properties.
Furthermore, Melanotan 2 and a comparable artificially delivered variation, known as PT-141, have been learned finally as a potential solution for the treatment of sexual brokenness; explicitly, male erectile dysfunction.
Molecular formula: C50H69N15O9
Molar Mass: 1024.180
CAS number: 121062-08-6
Melanotan 2 Structural Name: Lys10]α-MSH4-10-NH2, Ac-cyclo[Nle4, Asp5, D-Phe7
The Development of Melanotan 2
The initial making of the manufactured Melanotan 2 peptide can be credited to the University of Arizona. Over the span of research planned for building up a protection against skin malignant growth, the emphasis was put on building up a technique for invigorating common melanogenesis, or the normal creation oof melanin in the skin, without direct presentation to the possibly destructive bright radiation in daylight. At first, the University of Arizona specialists endeavored to legitimately oversee the normally happening hormone alpha-MSH so as to evoke this ideal outcome. Although this strategy exhibited promising results, it was determined that the naturally occurring MSH had a prohibitively short half-life to be of real use as a therapeutic remedy. However, the positive outcomes gathered from MSH organization empowered further investigation into the advancement of Melanotan 1 and Melanotan 2, which show comparable impacts while having an all-encompassing half-life for functional therapeutic utilization.
Melanotan 2 Studies and Further Information
Melanotan and Melanotan 2 are the two analogs of the peptide hormone alpha-melanocyte-animating hormone (α-MSH) that will in general initiate skin tanning. Unlike Melanotan 1, Melanotan 2 has been appeared to have Spanish fly properties, the extra impact of expanding drive. Melanotan 2 is a cyclic heptapeptide simple of the alpha-melanocyte-animating hormone (a-MSH).
The impacts of Melanotan 2 on the eating routine and nourishment admission of the research center mice have additionally been explored. It has been exhibited that the focal melanocortin (MC) has been actuated by Melanotan 2 when bolstered and prompted in the mice. The six-day treatment of Melanotan 2 has demonstrated that the peptide truly lessened the body weight and the fat tissue in the viscera of the mice and smothered the caloric intake of the organism. This has suggestions in clinical utilizations of the conceivable treatment to decrease starch or calorie admission particularly for overweight and large. Moreover, a similar report has additionally shown that there was a sustained increase in accessible oxygen utilization in obese animals. Melanotan 2 likewise helped decreased the level of serum insulin and the cholesterol levels when contrasted and the control medications. Moreover, it has been proposed that Melanotan 2 really brings down the level of acetylcholine A carboxylase expression and even prevented the decrease of carnitine and palmitoyltransferase I mRNA in muscle-type tissues by pair-bolstering in the muscles of the obese rodents. Moreover, the Melanotan 2 peptide actually increased the fat catabolism in the muscles and even improved cholesterol metabolism (Li et al. 2004).
α-Melanocyte-Stimulating Hormone Analogues (Melanotan Peptides)
α-Melanocyte-stimulating hormone (α-MSH) is a normally happening endogenous Melanotan peptide hormone of the melanocortin family, which is viewed as the most significant of the melanocyte-animating hormones when it comes to stimulating melanogenesis, a procedure which in well-evolved creatures is answerable for hair and skin pigmentation. α-MSH additionally assumes a job in sustaining conduct, vitality homeostasis, and sexual action (Bremelanotide and Melanotan 2). α-MSH is a nonselective agonist of melanocortin receptors MC1, MC3, MC4, and MC5. Melanotan 1 and Melanotan 2 initiate the MC1 receptor, which is answerable for impacts on skin pigmentation. Melanotan 2 and PT-141 both invigorate the MC3 and MC4 receptors which are answerable for the guideline of hunger, digestion, and sexual conduct. Be that as it may, PT-141 Bremelanotide doesn’t animate the MC1 receptor.
A few synthetic analogs of α-MSH have been investigated for their apparent photoprotective effects against ultraviolet (UV) radiation from the sun, namely, Melanotan (afamelanotide) and Melanotan II, referred to as Melanotan 2. Bremelanotide, another analog of α-MSH similar to Melanotan 2, is currently under development for the treatment of sexual dysfunction. All of these Melanotan peptides have fundamentally more noteworthy potencies than α-MSH, yet with unmistakable selectivity peptide profiles.
Buy Melanotan, Melanotan 2 and PT-141 Online Supplier
Swiss Chems™, the leading Melanotan 2 supplier, proudly offers a large selection of premium quality α-MSH analogs that are assayed at a minimum purity of 99%. We comprehend the incredible significance of buying just the highest quality Melanotan peptides online to guarantee the most extreme intensity (solidness) and immaculateness of your Melanotan 1, Melanotan 2 and PT-141 when you shop online.
All of our items are lab tried and the outcomes are occasionally distributed on the site.
Also known as: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2, Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 , Ac-cyclo[Nle4, Asp5,D-Phe7, Lys10]α-MSH4–10-NH2 m N-Acetyl-L-norleucyl-L-α-aspartyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-L-lysinamide (2→7)-lactam , PT-14, MT II
Peptides are stable at room temperature and can be stored in their initial packaging for several days to weeks. Otherwise, peptides can be kept at 4 °C or below. Peptides should be protected from intense light.